Research Advancements

Here are some of the latest research breakthroughs and advancements in the field of biomedical engineering and bioengineering

CRISPR-Based Therapies:

The development of CRISPR-Cas9 gene editing technology has revolutionized the field of biomedical engineering. It allows for precise and targeted modifications of genes, opening up possibilities for treating genetic diseases and developing personalized medicine approaches.

Genome Editing with CRISPR-Cas9

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Modifying the genetic material of a living cell has immense possibilities for advancing research in life sciences, enhancing biotechnology, and offering potential treatments for human diseases.

Techniques for editing genomes, such as zinc finger nucleases and Transcription Activator-Like Effector (TALE) Nucleases, have been available for some time. However, in 2013, these methods were rapidly surpassed by the engineered CRISPR-Cas9 system. This system, initially utilized by Feng Zhang of the Broad Institute and MIT for editing the genomes of mammals, demonstrated superior efficiency, effectiveness, and precision.

Some News and Updates

A Brief But Spectacular Take on the Future of CRISPR

April 18, 2023 Video, Interview, Jennifer Doudna

What’s Stopping Us from Curing Rare Diseases?

Freakonomics, M.D. | Freakonomics Radio Network | February 9, 2023

Organoid Technology:

Organoids are three-dimensional miniature organs grown in the laboratory from stem cells. Recent advancements in organoid technology have enabled the creation of more complex and functional organ models, providing valuable platforms for drug testing, disease modeling, and personalized medicine.

Brain Organoids

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Organoid technology offers several advantages in biomedical research and applications. These three-dimensional miniaturized organ models, derived from stem cells, closely mimic the structure and function of real human organs. Organoids provide a platform for studying organ development, disease mechanisms, and drug responses. They enable personalized medicine approaches, allowing researchers to test drug efficacy on patient-specific organoids. Organoids also hold promise in regenerative medicine, as they can be used to generate functional tissues and organs for transplantation. This technology accelerates research, reduces reliance on animal models, and has the potential to revolutionize healthcare.

Some News and Updates

Brain-Computer Interface (BCI):

A brain-computer interface (BCI), also known as a brain-machine interface (BMI) or neural interface, establishes direct communication between the brain and an external device. This concept was introduced by Professor Jacques Vidal in 1973 and has since seen a rapid increase in research and developments related to brain-to-computer communication. A typical BCI system comprises three key components: electrodes to record brain activity, a processing pipeline to interpret and decode the signals, and a computer or external device to carry out commands. BCIs can control various devices and serve five purposes: replacing, restoring, enhancing, supplementing, or improving human functions.

Brain Computer Interfaces

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Some News and Updates

Paralyzed man able to walk again with brain and spine implants

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Biofabrication and 3D Bioprinting:

Biofabrication techniques, particularly 3D bioprinting, have made remarkable progress. Through the use of bioinks and various cell types, researchers can now fabricate intricate tissues and organs. This cutting-edge technology holds tremendous promise for transforming regenerative medicine and organ transplantation. By enabling the creation of functional and personalized biological constructs, 3D bioprinting opens up new avenues for addressing organ shortage, studying disease mechanisms, and developing patient-specific treatments. It has the potential to revolutionize healthcare by offering innovative solutions for complex tissue engineering and regenerative therapies.

Biofabrication 3D Printing Human Parts I The Feed

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This information has been curated by our team in BioEduConnect

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